Senior Director Pharmacology

This is an exciting new position for a Biotech company based out of London, looking to strengthen the senior leadership team and scientific expertise by bringing onboard a Senior Director for Pharmacology to oversee all aspects of preclinical development for biologic and small molecule drug candidates into clinical development.

Responsibilities:

• Lead discovery teams by developing preclinical development strategies for drug candidates.
• Team up with scientists and external collaborators to develop preclinical screening strategies for discovery programs, which will include developing and optimizing new assays.
• Lead cross-functional discovery teams.
• Oversee and contribute to the preparation of preclinical sections of regulatory documents.
• Integrate and optimize automation strategies.
• Partner with the team to integrate analysis pipelines for cellular- and patient-derived data sets.
• Establish and Manage timelines, budgets, and resources for preclinical programs.

Requirements:

• Ph.D. in Pharmacology, Immunology, Oncology, Cell Biology or related field
• 10+ years of drug development experience
• Extensive experience in preclinical development
• Experience in leading discovery project teams to advance programs from early discovery to candidate selection and IND submission.
• Extensive knowledge of preclinical development processes, including pharmacology, toxicology, PK/PD, and translational science.
• Hands-on experience working with 3D cellular or tissue models to support discovery efforts
• Expertise in developing assays to support biologic and small molecule screening, including functional genomics-based target validation platforms
• Proven experience managing CROs and external collaborations
• Strong leadership and team-building capabilities, including experience managing other managers and influencing C-Suite leaders.

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